Basic principles of chemotherapy administration

Cytotoxic chemotherapy drugs are systemic therapies that aim to kill or slow the growth of tumor cells while being relatively sparing to normal cells.

The sensitivity of different tumor types to the actions of chemotherapy drugs varies widely among the cells of origin and across the range of drugs. In curable cancers, malignant cells can be many times more sensitive to cytotoxic drugs than the cells they have arisen from and, fortunately, more sensitive than the cells of the bone marrow. In the more common malignancies

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